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Metabolomic software improves workflow

Jacob Nthoiwa
By Jacob Nthoiwa, ITWeb journalist.
Johannesburg, 01 Jul 2011

Metabolomic software improves workflow

Laboratory Equipment.

The workflow integrates new application software - Thermo Scientific Sieve 2.0 differential expression analysis and Mass Frontier 7.0 structural elucidation software - with powerful new Thermo Scientific high-resolution accurate mass instruments: the Q Exactive high-performance benchtop quadrupole-Orbitrap LCMS/MS and the Orbitrap Elite hybrid mass spectrometer.

The new products accelerate even the most complex metabolomics studies. The complete solution can be seen at Thermo Scientific booth during the 7th International Conference of the Metabolomics Society in Cairns, Australia.

According to R&D Mag, the director of the demonstration and application laboratories of Thermo Fisher Scientific in North America says progress in metabolomics has been severely impeded by processing bottlenecks.

“The new capability in Sieve 2.0 software eliminates the most significant bottlenecks in current metabolomics data-processing, enabling scientists to find the most promising putative biomarkers quickly.”

Sieve software is an solution for label-free, semi-quantitative differential expression analysis of proteins, peptides and metabolites.

Using Sieve software to pre-filter the high-quality accurate mass generated by Thermo Scientific mass spectrometers greatly reduces the number of compounds that need to be identified, increasing the throughput of complex biomarker discovery experiments significantly.

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